The WNT inhibitory factor 1 (WIF1) gene, which is related to the tumor type pleomorphic salivary gland adenoma, was the gene with the greatest downregulation (16-fold change), while a member of the ETS family of transcription factors (ETV6), which is related to non-small cell lung cancer, had the joint smallest downregulation (0.64-fold change). The gene discussed is WIF1; the disease is non-small cell lung carcinoma.