In addition to adaptive immunity induced by the RASV vaccination, innate immunity associated with IκBζ could affect on the protection against Salmonella. To confirm this, we performed Salmonella infection in bone marrow derived macrophages obtained from WT and IκBζ−/− mice, and found that higher bacterial colonies were detected in IκBζ−/− mice as compared to WT mice (Supplementary Fig. 7). This evidence concerns the gene NFKBIZ and Salmonella Infections.