LAMC2 and neoplasm: Furthermore, serum LAMC2 levels can be used to significantly improve the diagnostic accuracy of using CA19-9 for PDAC patients, since the AUC for distinguishing between tumor and non-tumor tissues for the combined analysis of LAMC2 and CA19-9 (AUC=0.922, 0.792 and 0.888, respectively) in two of three cohorts were higher than the AUC values obtained for CA19-9 alone (AUC=0.863, 0.847 and 0.827, respectively; Figure 6J–6L).