On the other hand, in the TCGA dataset, we further confirm the significance of SPOCK1 in PCa progression, we collected 34 cases of primary tumors with matched non-tumor tissues from the cohort and found that SPOCK1 expression was also significantly higher in the tumor tissues compared to that in their paired normal tissues (Fig. 7c). The gene discussed is SPOCK1; the disease is posterior cortical atrophy.