For the effective treatment of cerebrovascular diseases and improves the cognitive and sensorimotor deficits, Ginsenoside Rb1 as also a major active component in PNS has the function on the modulation of the AKT/mTOR signaling pathway and down-regulation of caspase-3 in rats subjected to phototrombic stroke [26]. This evidence concerns the gene CASP3 and cerebrovascular disorder.