According to Oliveira et al., extracts of onion were able to reduce IL-4 and IL-5 levels in bronchoalveolar lavage of a murine model of asthma [63] and Kim et al. observed that extracts of A. hookeri decreased levels of TNF-α in nasal mucosa of a murine model of allergic rhinitis [64]. This evidence concerns the gene IL4 and allergic rhinitis.