LPXN was reported to be a fusion partner gene at exon 2 with exon 6 in ETV6 in relapsed acute myeloid leukemia (AML), and it played a crucial role in the enhanced proliferation response of the 32D myeloid cell line to granulocyte colony-stimulating factor (G-CSF) and C-X-C motif chemokine 12 (CXCL12) [152]. Here, LPXN is linked to acute myeloid leukemia.