Multiple pharmacological activities (Table 2) have been associated with olive biophenols (oleuropein, hydroxytyrosol, verbascoside, and quercetin) as potent antioxidants [74], which can scavenge superoxide anion, hydrogen peroxide, hypochlorous acid [75], with anti-atherogenic, anti-thrombotic, anti-inflammatory properties [74], and with inhibition the enzymes involved in AD pathogenesis (acetylcholinesterases, butyrylcholinesterases, beta-secretases, histones deacetylases) [99], and reducing Aβ toxicity [100]. This evidence concerns the gene ACHE and Alzheimer disease.