Having established a critical role for COL1A1 in the induction and/or enhancement of HCC cells invasion and migration through EMT deregulation, in vitro, we investigated probable links between COL1A1-induced metastatic phenotype and CSC-like phenotype using mRNA data (RNA Seq V2) from the provisional TCGA LIHC cohort consisting of 371 patients and 373 samples. Here, COL1A1 is linked to hepatocellular carcinoma.