NFKB1 and colitis: A previous study, using the dextran sulfate sodium-induced colitis (DSS-colitis) rat model, has demonstrated that resveratrol treatment (1 mg/kg/day for 25 days) provides beneficial effects on the colon, including altering the expression of inflammation-associated genes, protecting the colonic mucosa architecture, and modulating intracellular signaling such as NF-κB signaling pathway [84].