Increased secretion of chemokines and upregulation of adhesion molecules • CXCL9, CXCL10, and CXCL16 recruit primed effector T cells to the tumor microenvironment (TME) (24, 29, 30) • adhesion molecules on tumor vascular endothelium contribute to improved T cell infiltration (31). Here, CXCL16 is linked to neoplasm.