AKT1 and colonic disorder: The turmeric‐derived phytochemical, curcumin, is well known to be beneficial in IBD via inhibition of NF‐κB, p38 mitogen‐activated protein kinase, PI3K/AKT or inflammatory cytokine expression in mice and humans.29, 30, 31 In line with these studies, oral administration of curcumin protected against PM exposure‐induced inflammation in murine colons affording potential rescue from PM‐induced colonic disorders.