Moreover, CCSP‐2 protein secreted from tumor xenograft was successfully detected in the plasma of the xenografted mouse.18 Based on these findings, our group recently reported a method for fluorescent imaging of CCSP‐2 that enables more sensitive and specific detection of CRC during colonoscopy,19 thereby bolstering the potential use of CCSP‐2 as a blood‐based biomarker for CRC diagnosis. The gene discussed is VWA2; the disease is neoplasm.