Wrzesiński et al. (2015) reported a downregulation of TMEM72 in clear cell renal cell carcinoma. In recent studies, RTP3 (Zhou et al., 2007), SRHC (Zheng et al., 2015), TTC36 (Jiang et al., 2015), TNFAIP8L1 (Zhang et al., 2015), and ETNPPL (Ding et al., 2016) were reported to be downregulated in hepatocellular carcinoma. Also, RTKN2 was reported as novel candidate marker gene for idiopathic interstitial pneumonias (Steele et al., 2015). The gene discussed is RTKN2; the disease is hepatocellular carcinoma.