MAOA and endothelial dysfunction: More recently, it has been observed that MAO-A inhibition corrects endothelial dysfunction in mesenteric artery branches isolated from obese patients; indeed, ex vivo acute incubation of the arterial rings with the MAO-A inhibitor, clorgyline, significantly improved the endothelium-dependent relaxation and decreased the level of H2O2 (Adrian Sturza, unpublished data).