RPN1 and chronic kidney disease: Several loci with low frequency SNVs had suggestive evidence for association including SNVs located nearby RPN1 (p = 5.1 × 10-8), TYRP1 (p = 6.7 × 10-8), and LUC7L3 (p = 7.6 × 10-8) associated with CKD, and MIR4790 (p = 8.6 × 10-8) associated with ESKD.