CCL2: M1 macrophage recruitment (137).  GM-CSF: migration of Mo across the blood brain barrier (138, 139).  IFN-γ and α-B-crystallin: activation of microglia/Mφ of MS-affected brain tissue (140).  Acetylcholine-producing NK cells: kill and inactivate CCR2+Ly6Chi Mo (141). The gene discussed is CCR2; the disease is myeloid sarcoma.