Usually, in pemphigus vulgaris a mucosal-dominant phenotype (m-PV) is paralleled by autoantibodies against Dsg3 whereas epidermal involvement in PV (mc-PV) is in addition associated with formation of autoantibodies against Dsg1 which can also be found in pemphigus foliaceus (PF) (10). This evidence concerns the gene DSG1 and pemphigus vulgaris.