FLT3 and acute myeloid leukemia: In another murine model, the murine MAX.16H5 IgG1 also prolonged the survival of recipient C3H/HeN mice (receiving a TTG immune cell graft to induce GVHD) even if they were co-transplanted with myeloblast-like murine cell line 32D Clone 3 (32D) expressing human Fms like tyrosine kinase 3 with the internal tandem repeat duplication (FLT3ITD), which constitutes an aggressive acute myeloid leukemia (AML) cell line model (72).