Significantly high level (P < 0.05) of metabolic molecules like PP and C-peptide as well as inflammatory biomarkers like TNFα, sTNFRll, sICAM-1, TIMP-1, eotaxin, and sE-selectin were observed in DM group compared to the other groups (Figures 3A–D and Supplementary Figures 2A,B). This evidence concerns the gene TNF and diabetes mellitus.