Specifically, ART regulates the lncRNA UCA1/miR-184/BCL-2 axis, to inhibit prostate cancer (Zhou S. et al., 2017), while the has-circ-0043256/miR-1252/ITCH axis was involved in the treatment of non-small cell lung cancer by CA (Tian F. et al., 2017). Here, ITCH is linked to Familial prostate cancer.