p38MAPK/VEGF/Src kinase pathway is also involved in BBB disruption and vasogenic edema formation via inflammation-associated BBB dysfunction in subarchnoid hemorrhage (Han et al., 2018), ischemic stroke (Liang et al., 2009) and cold-induced brain injury, but not experimental pneumococcal meningitis (Paul et al., 2007). Here, VEGFA is linked to ischemic stroke.