Prevalence of infantile spasm, which was observed in all NF1 damaging DNM carriers identified in this study, in NF1 was reported as 0.54% (1/184) in ref. 44, 0.32% (2/630) in ref. 43, and 0.76% (2/260) in ref. 45. This evidence concerns the gene NF1 and infantile spasms.