Although the phenotype of different tumors are heterogeneous, the tumor microenvironment releases a number of factors, such as colony-stimulating factor-1, vascular endothelial growth factor (VEGF), C-C motif chemokine ligand 2, IL-4, IL-13, transforming growth factor-β, and IL-10, which can recruit monocytes and lead to M2-like differentiation [11, 12]. Here, VEGFA is linked to neoplasm.