HLA-DRB1 and triple-A syndrome: The Human Leukocyte Antigens (HLA) is an integral component of the immune response on which few genetic studies concentrated in the 1990s and early twenty-first century [14–20] different studies of alleles in various ethnic groups of the locus HLA-DRB1 demonstrated playing a role in the development of AAA [14–20], while one did not demonstrate this association [20].