They exhibited potent antitumor activity against a panel of tumor cell lines, including HCT-116 and HepG2, with IC50 values < 10 μg/mL, in addition to inhibitory activity against tumor growth-related tyrosine kinases, including FGFR3, IGF1R, PDGFRb, and TRKB [94]. The gene discussed is PDGFRB; the disease is neoplasm.