It was discovered that the concentration of atherogenic lipid metabolism values (LDL-C, LD-VLDL, Apo-B, TAG, Apo-B/Apo-A1, FFA) in the blood serum of patients with CAD on the background of patients with VO increased significantly and the content of anti-atherogenic fractions decreased (HDL-C and Apo-A1), relative to patients without VO (Table 4). This evidence concerns the gene APOB and coronary artery disorder.