MFRP and hyperopia: Apart from MFRP and TMEM98, high hyperopia is a frequent sign in other ocular or systemic diseases associated with mutations in several following genes, including PRSS56 (Gal et al. 2011), CRB1 (Abouzeid et al. 2006), LCA5 (den Hollander et al. 2007), IFT140 (Bifari et al. 2016), and KERA (Khan et al. 2004).