Then, Wilczynski et al. [154] directly investigated the role of MMP-9 in two animal models of epileptogenesis, namely, KA-evoked status epilepticus (SE, a condition known to provoke the development of epilepsy) and proconvulsive pentylenetetrazole (PTZ, a GABAA receptor antagonist) chemical kindling. The gene discussed is MMP9; the disease is status epilepticus.