These loci include the deleted in azoospermia family genes DAZ1, DAZ2, DAZ3, DAZ4, the Y-linked testis specific protein coding family genes TSPY1, TSPY2, TSPY3, TSPY4, TSPY8, the RNA binding motif protein Y-linked family 1 members RBMY1B, RBMY1E, RBMY1F, RBMY2FP, RBMY1J, and finally the Y-linked variable charge gene VCY. The gene discussed is RBMY1B; the disease is Azoospermia.