Rare cases with similar genetic profile were reported and were classified as diffuse large B-cell lymphoma.<h4>Conclusion</h4>The phenotype and genetic abnormalities of DLBCL with cyclin D1 overexpression can be complex and may be difficult to differentiate from blastoid and pleomorphic variants of mantle cell lymphoma. The gene discussed is CCND1; the disease is diffuse large B-cell lymphoma.