In LGGs, though patients with IDH-wildtype astrocytoma in low-expression group had longer (P = 0.059) OS than that of high-expression group in the CGGA database (Fig. 4a), the expression of eIF3i cannot stratify the OS of patients in TCGA dataset (P = 0.533, Fig. 4e). This evidence concerns the gene EIF3I and astrocytoma (excluding glioblastoma).