Our study is a first study that emphasized on prognostic value of mRNA expressions of CD marker genes in a systemic manner and we established that mRNA expression of IL2RA gene, among a selected list of CD marker genes, is a significant and independent prognostic biomarker in AML, in particular, in CBF and intermediate-risk AML subtypes. The gene discussed is IL2RA; the disease is acute myeloid leukemia.