Here, we showed that adipocytes cocultivated in the presence of breast cancer cells with different invasive capacities exhibited a decrease in the number and size of lipid droplets (Fig. 1a), which was accompanied by a dramatic reduction of the adipogenic markers, including AP2, PPAR-γ and C/EBP-α (Fig. 1b). The gene discussed is PPARG; the disease is breast carcinoma.