Baracco et al. [47] found that specific FPR1 antagonism reduced the efficacy of chemotherapy in a mouse breast cancer model via an immmunosupressive action, whilst this is not in a neuronal setting it may suggest that the multiple actions of FPR could play a role in vivo and limit the effectiveness of FPR1 antagonism in cancer chemotherapy. The gene discussed is FPR1; the disease is cancer.