Although the data from this publicly available database has been generated primarily from diseased individuals, not healthy controls, and from a locale geographically distinct to our MS cohort [96]; it suggests that RNF213 p.Asn2327Asp is a risk factor for MS, with carriers having more than twice the risk of developing disease (OR = 2.07; 95% CI = 1.15–3.72). This evidence concerns the gene RNF213 and myeloid sarcoma.