Based on the GEIPIA database, we also found that RHCG was downregulated in esophageal carcinoma, glioblastoma multiforme, head and neck squamous cell carcinoma, kidney renal clear cell and papillary cell carcinoma, brain lower grade glioma and so on, while upregulated in kidney chromophobe and lung squamous cell carcinoma. The gene discussed is RHCG; the disease is head and neck squamous cell carcinoma.