Although any direct link among UBE2V1 gene expression and NAFLD has not been reported, UBE2V1 is involved in non‐canonical IKK poly‐ubiquitination, which in turn activates NF‐kappa‐B cascade, which is one of the key pro‐inflammatory signalling pathways active in NASH.41 Here, UBE2V1 is linked to metabolic dysfunction-associated steatotic liver disease.