CASP3 and rheumatoid arthritis: On the other hand, six protein kinases related to survival, growth and apoptosis, (i.e., Bad, mTOR, Caspase 3, PARP, PRAS40 and S6 Ribosomal protein) were found phosphorylated in monocytes CD14+ from RA patients, while only 3 of those kinases were found phosphorylated in CD16+ monocytes (p < 0,05; Figure 7).