The binding of LPL to GPIHBP1 was specific: the LPL-specific goat antibody did not detect LPL in the capillaries of gliomas in Gpihbp1–/– mice, nor did it detect any LPL in macrophages or hippocampal neurons of Lpl–/–MCK-hLPL mice. The gene discussed is GPIHBP1; the disease is central nervous system cancer.