CTLA4 and inflammatory bowel disease: In inflammatory bowel disease mice, there was a reduction of CD4+ T cells producing IFN‐γ, an increased frequency of the putative regulatory population of T cells producing IL‐10, and an increment in the frequency of the regulatory markers GITR, CTLA‐4, PD‐1, CD73, and FoxP3, after treating with glucocorticoid (Sales‐Campos et al., 2017).