In our study, the vascular density was evaluated by examining the expression of FVIII in solid tumour masses, and while the mean vascular density in the tumour control group was calculated as 6.033, it was calculated as 3.000 in the treatment group administered with 25mg/kg curcumin, and as 1.866 in the group administered with 50mg/kg curcumin. This evidence concerns the gene F8 and neoplasm.