Ueki et al. (19) investigated the therapeutic effect of curcumin on the mice with renal inflammation which were agitated/stimulated by cisplatin; and it was stated that the serum TNF concentration in the group administered with curcumin (100mg/kg) along with cisplatin had decreased by 30%, whereas the serum TNF level had decreased by 10% in the group administered with only curcumin (50mg/kg), and that there was recovery in the renal dysfunctions as well. Here, TNF is linked to Abnormal renal physiology.