A modest but statistically significant (F = 6.114, df = 1,53, p = 0.017) increase was found for IL6ST mRNA in people with schizophrenia compared with controls (Fig. 1g), whereas IL8 and IL18 mRNAs (both F < 1.0, df = 1,52/53, p > 0.05) were unchanged (Fig. 1e, f). This evidence concerns the gene IL18 and schizophrenia.