Here, we also found that the activities of MMP-2 and MMP-9 are involved in glioblastoma cells’ invasion [31], as the activities of MMP-2 and MMP-9 were impaired in CrataBL-treated cocultures, but remained unchanged in CrataBL-treated MSC and U87 cell monocultures. This evidence concerns the gene MMP9 and glioblastoma.