KMT2A and leukemia: Literature search for leukemia cases reported with 11q23-25 amplifications and for which we could retrieve genetic information on the TP53 and MLL gene status also revealed that TP53 is frequently altered in 11q23-25 amplified leukemic samples lacking characteristic MLL rearrangements (Table S6), as suggested in prior studies (Andersen et al., 2001, Yip and So, 2013, Zatkova et al., 2009).