Literature search for leukemia cases reported with 11q23-25 amplifications and for which we could retrieve genetic information on the TP53 and MLL gene status also revealed that TP53 is frequently altered in 11q23-25 amplified leukemic samples lacking characteristic MLL rearrangements (Table S6), as suggested in prior studies (Andersen et al., 2001, Yip and So, 2013, Zatkova et al., 2009). This evidence concerns the gene TP53 and leukemia.