TP53 and T-cell non-Hodgkin lymphoma: Overall, when compared to early-stage Rag2−/−OTII p53−/− T cell lymphomas, the frequency of tumors carrying clonal 9qA4-5.3 amplification was significantly lower in late-stage Rag2−/−OTII p53−/− T cell lymphomas, as compared to early-stage Rag2−/−OTII p53−/− T cell lymphomas (p = 0.007) (Figure 3E).