NOTCH1 and T-cell non-Hodgkin lymphoma: In addition, although only 22 SVs were identified outside chromosome 9 in Rag2−/−p53−/− T cell lymphomas, among these, we identified four rearrangements affecting Notch1 and Pten, confirming that DNA lesions at these cancer genes can occur in the absence of RAG activity (Figure S4B).