In addition, although only 22 SVs were identified outside chromosome 9 in Rag2−/−p53−/− T cell lymphomas, among these, we identified four rearrangements affecting Notch1 and Pten, confirming that DNA lesions at these cancer genes can occur in the absence of RAG activity (Figure S4B). This evidence concerns the gene PTEN and T-cell non-Hodgkin lymphoma.