ARHGEF12 and cancer: Mouse 9qA4-5.3 corresponds to the syntenic 11q23.3-25 region in humans that contains 142 genes, including 11 genes (ARHGAP32, ARHGEF12, CBL, DDX6, ETS1, FLI1, HINFP, KCNJ5, MLL/KMT2A, PAFAH1B2, and PCSK7) reported within the network of cancer genes database (An et al., 2016) (Figure 4A).