Of note, in the subset of participants without diabetes, those with at least one copy of the MICA A5.1 allele remained at an apparent increased risk of pancreatic cancer, OR = 2.01 (, 95% CI: 1.04–3.89) implying that the observed association between A5.1 allele and pancreatic cancer was not driven by diabetes (S1 Table). This evidence concerns the gene MICA and pancreatic neoplasm.