MICA and neoplasm: Immune cells such as NK cells, gamma delta (γδ) T cells, and alpha beta (αβ) CD8 + T cells can target and eliminate pancreatic tumor cells when their NKG2D (natural-killer group 2, member D) receptors bind to the major histocompatibility complex class I-related chain A (MICA) protein expressed on tumor cells[5–7].