EGFR and cancer: Though we have hints that the cell membrane is not damaged as early as 48 h after treatment of cells with 213Bi-anti-EGFR-MAb (as deduced from microscopic observations)22, a current review on LDH in cancer cells strongly supports the hypothesis that the extracellular increase of LDH is most likely due to membrane leakage, induced by cytotoxic compounds39.