In other disease models, chemokines are involved in the fibrosis process of injured tissues, much like CCL5 contributes to liver fibrosis in non-alcoholic fatty liver disease progression (Li et al., 2017) and CXCR4 contributes to cardiac fibrosis in diabetes (Chu et al., 2015). This evidence concerns the gene CCL5 and metabolic dysfunction-associated steatotic liver disease.