In the present study, we investigated the cytotoxic effect of PT toward BCRP-transfected breast cancer cells, EGFR-mutated brain cancer cells, and colon cancer cells with a knockout mutation in the TP53. These cells exert resistance to conventional anticancer drugs (Kuete et al., 2016, 2017). This evidence concerns the gene ABCG2 and malignant colon neoplasm.