Of relevance, hnRNP A1 is also critically involved in the exon skipping of survival motor neuron 2 (SMN2; Kashima et al., 2007), involved in spinal muscular atrophy (SMA), another form of motor neuron disease and hnRNP A2/B1 has been implicated in Alzheimer’s disease (Mizukami et al., 2005). The gene discussed is SMN2; the disease is proximal spinal muscular atrophy.